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Best Touch of Death Centipede Spiritborn builds in Diablo 4 Vessel of Hatred

Diablo 4 Vessel of Hatred introduces the Spiritborn class which leverages the power of four different Spirit Guardians. Speccing into the Centipede gives you access to the busted Touch of Death build.

Diablo 4’s buildcrafting landscape has been turned upside down since the 2.0 update dropped alongside Vessel of Hatred and the Season of Hatred Rising. Sweeping changes to progression including a new level cap and a reworked Paragon system have impacted every player.

For those who purchased the expansion, you also have new mechanics such as Mercenaries and Runewords to consider. While overwhelming at first, the good news is this adds a tonne of depth to your build options.

This guide for the new Touch of Death Spiritborn build for Diablo 4 should illustrate that. We take you through options for PVE and PVP builds for the build and prepare you for endgame content like the Artificer’s Pit.

Get ready to poison enemies with Centipede skills.

Best Touch of Death Centipede Spiritborn leveling build in Diablo 4 Season 6

The Touch of Death Centipede Spiritborn build is exclusively for the Diablo 4 endgame and because of how it relies on certain Aspect synergies and Paragon skills, there isn’t really a workable variant for fast leveling.

For that reason, we recommend the Stinger Centipede Spiritborn build to level with. It uses some of the skills you’ll wind up with in your endgame Touch of Death build and is a handy way to learn when to cast them effectively.

Best setup for leveling

Best leveling rotation

  • Thunderspike
  • Stinger
  • Ravager
  • Rushing Claw
  • Armored Hide
  • The Hunter

Thunderspike will be your chief way of generating Vigor while applying Vulnerable to enemies to soften them up for your key damage abilities. You’ll also get some useful damage reduction from this thanks to the Diminishment passive when you allocate points there.

Stinger is your primary source of damage and a potent poisoning option thanks to some Legendary Aspects we’ll go over below. Pop Ravager to increase your damage output and increase Vigor generation.

Rushing Claw is used primarily as a mobility tool but with the Invasive augment, its a great tool for spamming damage as it loses its hindering cooldown. Reinforced Hide is here your defensive tool and also grants Unstoppable to shed crowd control.

Pop The Hunter ultimate often as a means of dealing big damage and stacking Ferocity of increased attack speed and Vigor generation. This should help you get off more Stingers to deal poison damage and use the Noxious Resonance Key Passive to pop that poison for insane AOE.

Best leveling Legendary Aspects

These Legendary Aspects will bolster your key damage skill and help generate resources to cast it more often. We have some for survivability thrown in.

Best leveling Mercenary

For this particular leveling build, Raehir is the best Mercenary to have on retainer. He provides Fortify for defense while harrying enemies with stun and a passive boost to Armor means you’ll get the most out of the Unyielding Hits Aspect’s damage boost when you use Reinforced Hide.

His Valiance skill also rescues you from big damage which means you’ll avoid one shots when trudging through Helltides for that extra Experience.

Best Touch of Death Centipede endgame build in Diablo 4 Season 6

Diablo 4 Touch of Death Centipede Spiritborn Endgame Build

The real Centipede Shennanigans begin with the endgame Spiritborn Touch of Death build.

Now that we’ve leveled effectively with the Stinger Centipede build, it’s time to swap over to the Touch of Death Centipede Spiritborn for endgame. This build focuses on synergizing the Touch of Death skill’s massive DOT and the Insatiable Aspect’s explosive swarms.

The Noxious Resonance Key Passive will pop your poison damage and trigger new swarms which makes up the bulk of your damage output. The Poised Touch of Death Augment turns the skill into a Core skill which then benefits from the Rod of Kepeleke’s insane Unique Aspect.

For your Primary Spirit Hall, you’ll want to use the Gorilla for access to Barrier as well as a near-permanent buff from the Aspect of Unyeilding Hits. Choose the Jaguar as your Secondary Spirit Hall for increased attack speed and a massive boost from the Harmony of Ebewaka Unique helm.

Combine all of this with the Ring of Midnight Sun and some extra sources of Vigor generation and the end result is a build that is able to constantly spam high-damage attacks thanks to unlimited resources and guaranteed crits.

Active skills

Passive Skills

Best endgame rotation

  • Touch of Death
  • Ravager
  • Armored Hide
  • Scourge
  • The Hunter
  • Counter Attack

Thanks to the Rod of Kepeleke, your Touch of Death is now a Basic skill that costs no resource, so you should be spamming it as often as possible to deal damage and generate swarms. Keep up Ravager and Armored Hide as often as possible for damage buffs and Unstoppable.

When faced with Elites or Bosses, pop Scourge to deal a massive burst of damage and refresh your resource. Use The Hunter Ultimate wherever possible to gain increased damage from Supremacy and Resolution.

When required for defense, Counter Attack will dodge almost all incoming damage thanks to a number of buffs to dodge chance. It also offers a critical chance bonus but it’s best saved for a pinch.

Paragon Boards and Glyphs

These are the Paragon Glyphs you’ll want to focus on for the Touch of Death Centipede Spiritborn build:

  • Canny: For every 5 Intelligence purchased within range, you deal +2.0% increased Non-physical damage.
  • Spirit: For every 5 Dexterity purchased within range, you deal +2.6% increased Critical Strike Damage.
  • Bane: For every 5 Strength purchased within range, you deal +2.0% increased Poison damage.
  • Revenge: Grants +20.0% bonus to all Rare nodes within range.
  • Colossal: For every 5 Strength purchased within range, you deal +2.0% increased damage with Gorilla Skills.

Best endgame items and equipment

Best endgame items and equipment

Best endgame Mercenary

For the same reasons he helped the leveling build, Raehir is the best Mercenary to hire for the Touch of Death Centipede Spiritborn. Primarily, the damage boosts he provides to the Unyielding Hits Aspect make him invaluable to keeping up your slaughter.

Best Touch of Death Centipede Spiritborn PvP build in Diablo 4 Season 6

Fortunately, you don’t need to make any alterations to the skills or equipment on your Touch of Death Centipede Spiritborn to take it into Diablo 4’s PVP. The resource generation and damage buffs of this build make it a monster against other players.

Whittle them down with DOT from Touch of Death and Scourge and then pop them unceremoniously with the Noxious Resonance Key Passive. It’s simplicity itself.

That’s everything you need to know to build your Touch of Death Centipede Spiritborn in Diablo 4 Vessel of Hatred. Check out our Spiritborn build tier list if you want to see how your chosen loadout stacks up.


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